ABSTRACT
ABSTRACT The Market share of electrical vehicles has been rising in the past few years and tends to rise even more. According to the International Energy Agency, an increase of 50% in the number of electrical vehicles is expected. Whilst that increase is beneficial from a greenhouse gases emissions drop point of view, that rise could, on the other hand, represent a major increase in the electrical power consumption. Besides, other problems such as harmonics and overloads could emerge from the massive connection of electrical vehicles to the electrical grid. Therefore, it is necessary to perform studies and simulations in order to estimate those problems and to mitigate the problems related to the inevitable expansion of the electric vehicle fleet in the near future. The present work intends to run simulations so as to identify the main effects of the electrification of the vehicular fleet in the city of Curitiba, as well as understand how the provision of ancillary services through the electrical vehicles can help in the process.
Subject(s)
Automobiles , Simulation Exercise/methods , Energy Supply , Electrical Equipment and Supplies , BrazilABSTRACT
PURPOSE: To investigate the protective effects of pentoxifylline against lung injury observed after dorsal scald in aged animals. METHODS: Adult (eight months old) and aged (20 months old) rats were subjected to thermal injury or sham procedure. The six hours post-trauma animals received pentoxifylline and after 24 hours were euthanatized and lung tissue samples collectedted. The bronchoalveolar lavage fluid was evaluated for total protein content and tumor necrosis factor-alpha cytokine. Malondialdehyde and myeloperoxidase activety in the lung homogenate were measured and a histological lung examination was undertaken. RESULTS: Burn injury induced oxidative stress in lung homogenate was higher in elderly-burned rats compared to adult-burned rats (p<0.001). Total protein and cytokine in bronchoalveolar lavage increased in the elderly-burned group when compared to the adult-burned group (p<0.001). All parameters decreased in bolth groups treated with pentoxifylline (p<0.05). CONCLUSIONS: The injury was augmented in elderly rats when compared to adult rats. Damage was reduced with the use of pentoxifylline, however further studies are needed to evaluate the dose-response of the drug.